https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Genome-wide association and functional follow-up reveals new loci for kidney function https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15141 Wed 11 Apr 2018 13:54:12 AEST ]]> Novel blood pressure locus and gene discovery using genome-wide association study and expression data sets from blood and the kidney https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34209 Wed 09 Feb 2022 15:53:11 AEDT ]]> New genetic loci link adipose and insulin biology to body fat distribution https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28089 Sat 24 Mar 2018 07:39:47 AEDT ]]> Genetic studies of body mass index yield new insights for obesity biology https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27460 −8), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ~2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.]]> Sat 24 Mar 2018 07:32:44 AEDT ]]> Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30005 Mon 17 Oct 2022 12:06:14 AEDT ]]>